To apply a preset to the Native PHY IP core, double-click on the preset name. When you apply a preset, all relevant options and parameters are set in the current instance of the Native PHY IP core. For example, selecting the Interlaken preset enables all parameters and ports that the Interlaken protocol requires.
Selecting a preset does not prevent you from changing any parameter to meet the requirements of your design. Any changes that you make are validated by the design rules for the transceiver configuration rules you specified, not the selected preset.