7.4.5. Package Deskew
If you do not enable the package deskew option, the Intel® Quartus® Prime software uses the package delay numbers to adjust skews on the appropriate signals; you do not need to adjust for package delays on the board traces. If you do enable the package deskew option, the Intel® Quartus® Prime software does not use the package delay numbers for timing analysis, and you must deskew the package delays with the board traces for the appropriate signals for your design.
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