Due to a problem in the Intel® Quartus® Prime Pro Edition software version 21.1, an invalid .jic file will be generated when incompatible frequencies are used for ACTIVE_SERIAL_CLOCK and DEVICE_INITIALIZATION_CLOCK in your Quartus Settings File (.qsf). The configuration flow will fail using this .jic file.
To avoid this error, make sure your .qsf file has a compatible set of frequencies for ACTIVE_SERIAL_CLOCK and DEVICE_INITIALIZATION_CLOCK. The valid AS_CLK settings can be found in the Intel® Stratix® 10 Configuration User Guide.
A patch is available to check for valid frequencies for ACTIVE_SERIAL_CLOCK and DEVICE_INITIALIZATION_CLOCK in the Quartus Settings File (.qsf).
Download and install Patch 0.06 from the appropriate link below.
After installing patch 0.06, in your next compilation with an incompatible set of frequencies you will get an error message during the Assembler stage saying "The active serial clock is not supported in device initialization clock"
This problem is fixed starting with the Intel® Quartus® Prime Pro Edition software version 21.2.