Due to a limitation of all the Video IP cores, you will see either swapped colors (Cb/Cr are swapped on the Avalon-ST bus, Red and Blue colors swapped on the display) or distorted images if you use odd frame widths when processing 4:2:2 data.
To work around this issue you must use even frame widths when processing 4:2:2 data.
Further, the clipper requires even clip start offsets and the Mixer requires even offsets when using 4:2:2 data.
This behavior is not planned to be changed in any future release of the Quartus® Prime software.