Intel® Optane™ memory should be disabled before applying the OS or BIOS updates, and then re-enabled again once the process is complete. Follow the steps below to disable the module:
When OS updates are initiated, the system reboots multiple times in order to complete the update process. Although not common, it is possible that the Intel® Optane™ memory configuration changes when the system reboots during the OS update process. This may conflict the system in fetching the data from the HDD/SSD being accelerated, which causes the system to crash.
When a BIOS update takes place, most of the time the BIOS settings are returned back to default. Therefore SATA mode would be changed back to AHCI, which conflicts with the Intel® Optane™ memory configuration and could cause booting issues.
If the OS or BIOS update was applied while still having the Intel® Optane™ memory enabled and booting issues occur, the best recommendation is to try to re-configure the Intel® Optane™ memory setup. Unfortunately, if re-configuring the BIOS for Intel® Optane™ memory acceleration does not fix the issue, it may be necessary to re-install the OS and format the Intel® Optane™ memory. Always back up your data before doing any system changes.