In Intel® Stratix® 10 devices, each x4 DQ group in a 3V I/O bank shares the same Output Enable (OE) and therefore you cannot split the OE within a x4 DQ group.
However, when you implement the following construct and place them in the same x4 DQ group:
INOUT_1 < = ‘0’ when ENABLE_1 =’0’ else ‘Z’;
INOUT_2 < = ‘0’ when ENABLE_2 =’0’ else ‘Z’;
The Intel® Quartus® Prime Pro Edition Software will implement the I/O as Open Drain and modify the RTL by disconnecting the OE and move it to DATA IN. This will result in both I/O buffers having their OE port tied to GND, allowing them to be placed in the same nibble.
This is an expected behavior.