Description
No, when you use EPCQ or EPCQA quad-serial configuration device for AS configuration, you can't connect VCCIO of I/O bank 1 to 2.5V in Cyclone® III, Cyclone IV or Cyclone 10 LP device.
This is because the minimum VOH of the FPGA device is insufficient for driving EPCQ or EPCQA input pins.
Resolution
Use 3.0V or 3.3V for Bank 1 VCCIO in Cyclone III, Cyclone IV and Cyclone 10 LP devices when AS configuration with EPCQ or EPCQA devices is used.