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| Improving the Odds |
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How do high school students prepare for a
lifetime of scientific achievement? Several STS finalists spent their summer at
the Research Science Institute, honing research and presentation skills,
conducting experiments in collegial laboratories, and learning from some of the
best mentors in science.
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From studying the migration of cells through a microscope to probing the expanses of space, the projects presented at this year's STS competition run the gamut. But all of these projects demonstrate that their creators share common qualities: curiosity, inventiveness, and perseverance.
This was abundantly clear when this year's group of promising young scientists and mathematicians gathered beneath the grand rotunda of the National Academy of Sciences for two days in March to present their projects to the public.
Here's a look at some of the research projects conducted by the 2006 Intel STS finalists.
Sheela Krishnan
Sheela Krishnan became interested in bees on a visit to
India a few years ago when she first learned of the natural health benefits of
honey. Curious about the antimicrobial properties of the substance, Krishnan
returned home to Suffern, New York, and researched the subject. When she came
across an article on American Foulbrood Disease (AFD), a virulent bacterial
disease that decimates bee populations worldwide and causes severe economic
loss to farmers, she was inspired to find a way to treat the disease.
Working under her mentor, Dr. Randy Worobo, at Cornell
University, the Suffern High School student spent the next two years examining
bacteria isolated from the honey sacs of honeybees, including the bacteria
behind AFD. In short, she says, "I took the bacteria from the stomachs of
honeybees and tested them against the bacteria that causes the disease. I found
that a number of them actually inhibited its growth, which means that they may
serve as a potential cure for the disease."
Based on her findings, Krishnan created a cocktail for
preventative therapy against AFD in honeybees. It has "far-reaching
implications," she says, "because it can potentially lead to a safe,
non-invasive and inexpensive preventive measure to combat the lethal AFB
disease in vivo."
Next year, Krishnan plans to study medicine and anthropology
at Brown, with the ultimate goal of becoming a physician. "I feel is it
important to learn about the cultures and beliefs of people in order to better
administer medicine to them," she says.
Lucas Edward Möller
Seven years ago, a contest sponsored by The Planetary
Society and NASA's Jet Propulsion Laboratory inspired then-ten-year-old Lucas
Möller to ponder the surface of Mars.
Fast forward to the present where Möller, now 17 and a senior
at Moscow High School in Moscow, Idaho, is conducting ever more serious
investigations of the dusty red planet. His STS entry investigates new
approaches for understanding dust behavior on Mars. "The project is the
equivalent of piling sand on top of a basketball, and looking at how much sand
collects on the top of that basketball, but instead I am using Mars dust and a
small stainless steel sphere," Möller explains. By examining the dust
collection patterns on the sphere and how the particles interact with each
other, one can determine qualities of the dust itself: their size and shape,
what they are made of.
The project also has applications closer to home. Möller's
research in granular physics may be of value in industrial processes involving
mineral ores, as well as agricultural commodity and industrial powder
transport. Additionally, it may apply to the analysis of landslides,
avalanches, and shifting sand dunes.
Möller hopes to attend Stanford or the University of
Washington, and ultimately pursue a career in bio-engineering and space
science. "Human space exploration would be a great field to go into," he says.
Eric Allan Meyerowitz
Eric Meyerowitz's research project analyzes two peptides with opposite functionality, but that are very similar in structure. His work probes for reasons behind the disparate functions, focusing on improving knowledge of the locations in the membrane where binding occurs. His findings were achieved, in large part, using nuclear magnetic resonance technology.
The results of his research could improve the specificity of drug applications, Meyerowitz explains. For example, drugs intended for neurological treatment often carry gastrointestinal side effects as a result of similar binding properties. Knowledge of structure and binding properties could be used to decrease such side effects.
Meyerowitz plans to continue his studies next year at Columbia, Harvard, or Stanford. Ultimately, he hopes to pursue a career as a physician and research scientist. "I would like to contribute to the alleviation of suffering, due to malnutrition and disease, in third-world countries," he says.

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